mailwal

Why women’s brains age differently

Dr. Mark Hyman
Hi there,
Most women expect their bodies to change as estrogen declines.
Far fewer are told that their brains change too.
And some of those changes may be more significant than you think. In one study, the brains of middle-aged and older women appeared to age a stunning 5–6 years faster than those of middle-aged and older men.
That matters because women also face a higher lifetime risk of Alzheimer’s disease, the most common cause of dementia. Roughly 1 in 5 women will eventually develop the disease, compared with about 1 in 10 men.
But brain decline isn't inevitable.
Understanding what changes in the female brain—and the role estrogen may play—gives you opportunities to support it differently during this stage of life.
That’s exactly what you’ll learn about here. Plus, get my top 8 strategies for both women and men to help protect your brain as you age.
WE'RE GRATEFUL FOR OUR SPONSOR PIQUE

I think about skin health as a reflection of what’s happening throughout the body. What I eat, how I sleep, how well I hydrate, and how I manage oxidative stress all influence the health and appearance of my skin. For me, supporting it from within is part of my broader daily routine.

Pique’s Radiant Skin Duo fits naturally into that approach. B·T Fountain combines electrolytes with clinically studied ceramides, ultra-low molecular weight hyaluronic acid, and silica to support hydration and smoother, plumper-looking skin. Sun Goddess Matcha provides antioxidant catechins, including EGCG, that help defend against oxidative stress and support existing collagen.

I’ve made both part of my routine because they turn skin support into two daily rituals I can maintain. With colder weather, travel, late nights, and holiday events approaching, that consistency becomes even more important.

If you want your skin looking its best through the holidays, don’t wait until December to start. Pique is offering my readers 20% off the Radiant Skin Duo for life when you subscribe through my link.

LONGEVITY SECRETS
MORE WAYS TO CONNECT
The doctor-designed program that helps you feel your best in just days. Learn more.

A nutrition-based approach to better mental, emotional, and cognitive health. Learn more.

Get 160+ lab tests detecting 1000+ conditions for just $1 a day. Learn more.
My top recommendations for improving your nutrition and health. Learn more.
Every Saturday, I share my favorite healthy, whole food recipes. Learn more.

A clear look at how today’s food system impacts your health—and what to do. Learn more.

What did you think about this week's Longevity Journal? Send your feedback to [email protected].
AFFILIATE DISCLAIMER
SOME OF THE LINKS IN THIS NEWSLETTER ARE AFFILIATE LINKS. THIS MEANS IF YOU CLICK AND MAKE A PURCHASE, I MAY EARN A COMMISSION—AT NO EXTRA COST TO YOU. I ONLY RECOMMEND PRODUCTS I TRULY USE AND TRUST.

MEDICAL DISCLAIMER
THIS CONTENT IS FOR INFORMATIONAL PURPOSES ONLY AND DOES NOT CONSTITUTE MEDICAL ADVICE, DIAGNOSIS, OR TREATMENT. ALWAYS CONSULT A QUALIFIED HEALTHCARE PROVIDER WITH ANY QUESTIONS ABOUT YOUR HEALTH.
© 2026 Dr. Hyman. All Rights Reserved. Terms of Use and Privacy Policy.
55 Pittsfield Road Ste 9 Lenox, MA 01240